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Innovative Cell Therapy Offers Hope for Refractory CD30-Positive Lymphoma Patients A groundbreaking study has unveiled a novel cell therapy strategy that employs cord blood-derived natural killer (NK) cells pre-complexed with AFM13, a bispecific antibody targeting both CD30 and CD16A. This innovative approach shows promising safety profiles and high response rates in patients suffering from refractory CD30-positive lymphomas, particularly high-risk groups that have not responded to traditional treatments. The work is notably spearheaded by researchers at The University of Texas MD Anderson Cancer Center and aims to transform the therapeutic landscape for patients battling these aggressive malignancies. The Phase I trial…

A groundbreaking discovery from the University of Massachusetts Amherst has unveiled a new class of materials known as “shape-recovering liquids.” This research, spearheaded by graduate student Anthony Raykh and his team, challenges traditional expectations set by the laws of thermodynamics, providing insights into the behavior of mixtures involving oil, water, and magnetized particles. The findings, published in the esteemed journal Nature Physics, showcase a remarkable phenomenon where a mixture, when shaken, forms a consistent and elegant urn-shaped structure that seems to defy natural expectations. Raykh’s journey began with an experiment that feels almost culinary in nature. In mixing oil, water,…

Storm forecasting is undergoing a significant transformation driven by innovative research that focuses not just on atmospheric conditions but also on land surface factors. This intersection of meteorology and environmental science is set to revolutionize early warning systems in vulnerable tropical regions that face the brunt of climate change impacts. By integrating new methodologies into their traditional forecasts, scientists are paving the way for communities to better prepare for the potentially catastrophic effects of severe weather events. A recent study conducted by the UK Centre for Ecology & Hydrology (UKCEH) unveils a groundbreaking approach to understanding storm dynamics. It emphasizes…

Welcome to our monthly trawl for developmental and stem cell biology (and related) preprints. The preprints this month are hosted on bioRxiv and arXiv – use these links below to get to the section you want: Developmental biology Cell Biology Modelling Tools & Resources Research practice and education | Patterning & signalling Notch-mediated regulation of β-Catenin-TCF activity instructs anteroposterior neuron positioning in C. elegans Wesley Chan, Justin Evans, Tony Roenspies, Jonathan D. Rumley, John I. Murray, Antonio Colavita MicroRNA miR-196a controls neural crest patterning by repressing immature neural ectoderm programs in Xenopus embryos Alice M. Godden, Nicole Ward, Méghane Sittewelle,…

Antibiotic resistance poses one of the most significant threats to global health in contemporary times. Researchers at Umeå University in Sweden have revealed new insights into this alarming issue, suggesting that the mechanisms bacteria employ to fend off viral attacks may also provide crucial information on how antibiotic resistance develops. With the potential to surpass cancer mortality rates in a few decades, understanding the intricacies of bacterial defense mechanisms is imperative to inform future treatment strategies for antibiotic-resistant infections. The implications of this discovery could herald a new dawn in combating a problem that endangers millions of lives around the…

Milan, Italy – April 4, 2025 – In a significant finding presented at the ESC Preventive Cardiology 2025 conference, researchers have unveiled that two distinct plant-based diets, the Planetary Health Diet (PHD) and the Mediterranean Diet, offer comparable advantages in reducing all-cause mortality while maintaining a minimal environmental footprint. This research is particularly pertinent in a context where diet is increasingly recognized as a pivotal factor influencing cardiovascular health and overall longevity. The alarming statistics from the European region indicate that dietary choices contribute substantially to cardiovascular disease mortality. Estimates reveal that optimizing diet could prevent one in every five…

Cell therapies are at the cutting edge of personalized medicine but as demand for these therapies grows, how will the industry scale manufacturing to meet patient needs?Fabian Gerlinghaus is co-founder and CEO of Cellares. He and his team have developed the Cell Shuttle, an advanced cell manufacturing technology that is already demonstrating the potential to 10x cell yields while halving costs for pharmaceuticals companies and innovators. Is this the future for smart cell manufacturing?0:52     A starting point in aeronautical engineering2:43     First steps into biotech5:25     Co-founding Cellares6:30     The problem that Cellares addresses11:02   Best practice bio manufacturing17:14…

In a significant development for the disinfectant industry, Singapore has introduced a pioneering national standard known as SS 705, designed to enhance hygiene and infection control in the wake of heightened public health awareness following the COVID-19 pandemic. This new standard represents a comprehensive assessment methodology to evaluate the efficacy and longevity of various surface disinfectants and coatings against antibacterial, antifungal, and antiviral agents. By establishing a scientific, evidence-based framework, SS 705 aims not only to facilitate manufacturers in verifying their product claims but also to empower regulatory bodies in maintaining consistent product quality. The rapid evolution of the antimicrobial…

Newsletter Signup – Under Article / In Page”*” indicates required fields Do you associate biotech with space conquest? Space isn’t just about rockets and satellites – it’s an increasingly valuable environment for running biomedical experiments that aren’t possible on Earth. Under microgravity, biological systems behave differently, and that difference is exactly what makes space so useful for drug discovery and disease research. And Exobiosphere, a Luxembourg-based contract and research organization (CRO) is leveraging this environment.Today, Exobiosphere completed an €2 million ($2.2 million) seed round to develop its microgravity-enabled drug discovery platform. The company is backed by the Luxembourg Space Agency…

Antibiotic resistance tends to stabilize over time, according to a study published April 3, 2025 in the open-access journal PLOS Pathogens by Sonja Lehtinen from the University of Lausanne, Switzerland, and colleagues.  Antibiotic resistance is a major public health concern, contributing to an estimated 5 million deaths per year. Understanding long-term resistance patterns could help public health researchers to monitor and characterize drug resistance as well as inform the impact of interventions on resistance. In this study, researchers analyzed drug resistance in more than 3 million bacterial samples collected across 30 countries in Europe from 1998 to 2019. Samples encompassed…