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The appropriate utilization of animals within non-clinical research is always on the minds of drug developers. Lovelace Biomedical is always working with its team of experts to stay in touch with the current regulatory landscape and evaluating novel approaches to reduce the number of animals required in drug development. With the recent changes in the FDA Modernization Act Lovelace’s approach continues to evolve and some details can be found in their recent article with AAPS News Magazine: Bringing Clarity and Perspective to the FDA Modernization Act 2.0. Halo, sobat pengemar slots pernahkah denger istilah “slot gaco”? jika belum, siap-siap jatuh…

Yesterday evening, I had dinner with my friend Mark Moffett. As always, we had a wide-ranging discussion about human and animal behavior and this reminded me just how insightful his work on animal societies is, and how much his writing has impacted my views on human social evolution. With permission, I reprint below a review that I wrote a few years ago for Skeptic Magazine on Mark’s book The Human Swarm. Although the book is a very detailed review of mountains of scientific work, both Mark’s own and his peers around the world, he writes in a very accessible and…

Lovelace Biomedical has an over 70-year history in the area of respiratory drug delivery. Throughout this history, the question of how to build relationships between non-clinical and clinical doses has always come up. Philip Kuehl is a co-author of a recent article published in the Journal of Aerosol Medicine and Pulmonary Drug Delivery that details this process in a direct manner. If you wish to learn more about inhalation dosimetry between species reach out to an expert at Lovelace Biomedical. View the full article here: https://www.liebertpub.com/doi/10.1089/jamp.2023.0041 Download the Full Article The post Philip Kuehl Co-Authors Article in the Journal of…

No such thing as a standard career path – an interview with Karen Liu Karen Liu is Professor of Genetics and Development at King’s College London, UK. She did English and architecture as an undergrad and worked in an architectural firm for a couple of years before deciding to pursue a scientific career. We had a chat with Karen to find out more about her switch from architecture to science, and how her own experience has influenced how she guides early career scientists through their career journeys today. Can you briefly tell us about your career path so far? I’m…

Post provided by Vitek Jirinec In 2013, I found myself knee-deep in the marshes and forests of southeastern Virginia, USA, embarking on what would become an unpredictable journey in my career. Fresh into my graduate thesis at the College of William & Mary under the guidance of Matthias Leu, the plan was studying the habitat use of Wood Thrushes—a species that is often researched, but as I would come to learn, doesn’t always cooperate with research plans. The start of something unexpected To earn my keep with Matthias, I also conducted his annual point count surveys, but the heart of…

Inhalation drug delivery continues to evolve and develop for the delivery of novel compounds. In a recent publication, Lovelace Biomedical supported TFF Pharmaceuticals with their thin film freezing technology for delivery of an mAb against SARS-CoV2. These technologies, along with validated animal models, enable non-clinical evaluation of dry powder mAb’s. If you are interested in how to evaluate your formulation reach out to Lovelace Biomedical. Hello, sobat pencinta slots pernahkah mendengar semboyan “slot gaco”? Kalau belum, siap-siap jatuh hati sama program ini. slot gaco merupakan mesin slots yang selalu memberi kemenangan. Yup, mesin-mesin ini bisa dikatakan adalah jagoannya tuk bawa…

The massive presence of disorder and variability challenges the traditional metaphor of the developmental process as a perfectly executed program leading to precise mechanisms at every level [1,2]. Yet, the final outcome —the organism— remains both astonishingly complex and remarkably reproducible. This paradox piqued the interest of Dimitri Fabrèges and Takashi Hiiragi. Back then, around 2017, Takashi was research group leader at the EMBL Heidelberg, and Dimitri a postdoc in his group. They began to explore the idea of disorder and variability from a provoking viewpoint: instead of undermining the precision of the developmental process, randomness and variability might actually…

Image credit: geralt, via Pixabay. In a study of brain imaging (fMRI) changes in over 800 people, both while they were active and while they were resting, University of Würzburg researchers found that the whole brain is active more often than we may think. They distinguished three types of intelligence that we use: Fluid intelligence refers to the ability to solve logical problems, recognize patterns and process new information, independent of existing knowledge or learned skills. Crystallized intelligence encompasses the knowledge and skills that a person acquires over the course of their life. This includes general knowledge, experience and understanding of language…

isbscience.org/news/2024/09/04/how-microbes-evolve-to-spatially-divide-and-conquer-an-environment/  Posted on September 4, 2024 This customized fluidized bed reactor uses an up-flow current to “fluidize” a bed of solid particles into a suspension, similar to how soil particles are suspended in flowing groundwater in the subsurface. Methane is produced naturally – expelled by wetlands, wild animals, and other sources – and via manmade sources like agriculture and fossil fuel production and use. While not as abundant as carbon dioxide in our atmosphere, methane traps significantly more heat, making it a critical-to-understand component in climate change.  Researchers in the Institute for Systems Biology’s Baliga Lab examined representative organisms of two classes…

Introducing a new careers interview series Is there such thing as a standard career path for a scientist? Some people find fulfilment in pursuing a PhD, postdoc, then starting their own research group; others may have second thoughts or may be drawn by other interests and aspirations.   In this new series, we chatted to several developmental biologists who have had vastly different career trajectories. This interview series was inspired by this 2013 post from Kara Cerveny, who went back into academia as an assistant professor after a stint as a scientific editor. Below is a sneak peak of the…